Predigen's scientific team has published extensively in the area of host response.

 The Predigen team has collectively published over 400 articles in peer reviewed journals, many of which are listed below.

EPHRAIM TSALIK, MD, PhD – Predigen Co-Founder

Dr. Ephraim Tsalik is an Associate Professor of Medicine in the Center for Applied Genomics & Precision Medicine and the Division of Infectious Diseases at Duke University School of Medicine. Dr. Tsalik is also a faculty member in the Department of Molecular Genetics and Microbiology at Duke.  In addition, he is a Staff Physician in the Emergency Department Service of the Durham VA Health Care System.

Dr. Tsalik’s research has focused on the development, evaluation, and promotion of diagnostics for acute infectious disease. He has made use of systems biology approaches to characterize the host response to infection, using these fi­ndings to drive the development of diagnostic and prognostic assays. Specifi­c areas of interest include the differentiation of infectious from non-infectious disease; bacterial vs. viral infection; and using molecular data to rede­fine the sepsis syndrome. He is also the Associate Director of Diagnostics for the NIH-funded Antibacterial Resistance Leadership Group, where he interfaces with industry and academic partners to advance diagnostics development. Dr. Tsalik has engaged with regulatory authorities such as the FDA regarding host response biomarkers, speaking at their public workshop on Non-Microbial Biomarkers of Infection for In Vitro Diagnostic Device Use. He served on the NHLBI Working Group on Pneumonia, offering guidance on the host response to pnemonia.

View Ephraim Tsalisk's Bibliography

GEOFFREY GINSBURG, MD, PhD – Predigen Co-Founder and Biomeme Scientific Advisory Board Member

Dr. Geoffrey Ginsburg is the founding director for the Duke Center for Applied Genomics & Precision Medicine and of Duke MEDx. He also founded Genomic Medicine in the Duke Institute for Genome Sciences & Policy and the Center for Personalized Medicine, established in the Duke University Health System. He is Professor of Medicine, Pathology, and Biomedical Engineering. Dr. Ginsburg has pioneered translational genomics, and has led the development of predictive models for common, complex diseases using high dimensional genomic data. He is an internationally recognized expert in genomics and personalized medicine with over 200 published papers, and funding from NIH, DOD, DARPA, the Gates Foundation, and industry.

He has been a member of the Secretary of Veterans Affairs Advisory Council on Genomic Medicine, a member of the NIGMS External Scientific Panel for the Pharmacogenomics Research Network, the Board of External Experts for the NHLBI, the National Advisory Council for Human Genome Research at NIH, the Advisory Council for the National Center for Advancing Translational Sciences at NIH, and the World Economic Forum’s Global Agenda Council on The Future of the Health Sector. He is co-chair of the National Academies Roundtable on Genomics and Precision Health, founder of the Global Genomic Medicine Collaborative, and a member of the Advisory Committee to the Director of NIH.

View Geoffrey Ginsburg's Bibliography


CHRISTOPHER WOODS, MD, MPH – Predigen Co-Founder and Biomeme Scientific Advisory Board Member

Dr. Christopher Woods is the Co-Director of the Hubert-Yeargan Center for Global Health. He is a professor in the Departments of Medicine and Pathology at Duke University; an adjunct professor in Epidemiology at the University of North Carolina at Chapel Hill School of Public Health; and an adjunct professor in the Emerging Infections Program at the Duke-National University of Singapore Graduate Medical School. Clinically, he serves as Chief of Infectious Diseases and clinical microbiology, and hospital epidemiologist for the Durham VA Health Care System. Dr. Woods is board-certified in internal medicine, infectious diseases, and medical microbiology. He currently serves as the Director of Graduate Studies and the MSc for Global Health in the Duke Global Health Institute.

Dr. Woods has published over 130 peer-reviewed articles and has a particular interest in development of medical microbiology capacity in the developing world and the epidemiology of emerging and re-emerging infectious diseases. His research focuses on the development of novel diagnostic approaches to infectious disease and the potential for interspecies transmission of pathogens. His genomic approach to harnessing the host response for diagnosis of infectious diseases has been called a paradigm shift in the field. Dr. Woods is a partner in the Southeastern Center for Emerging Biological Threats, core PI of the Southeastern Research Center for Excellence on Emerging Infections and Biodefense, and a leader in the NIH-funded Vaccine and Therapeutics Evaluation Unit at Duke.

View Christopher Woods' Bibliography


Highlighted Publications:

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